What Does Isaiah 63:10 Mean?

But they rebelled, and pained his Set-Apart Breath. So he was overturned to be their enemy, and he fought against them.
Isaiah 63:10 · SDV
Key words are shown with the Hebrew or Greek and what each word meant.

Selah Decoded Version The Selah Decoded Version renders what the Hebrew and Greek words meant to the people who first heard them.

This verse in the King James

King James wording
But they rebelled, and vexed his holy Spirit: therefore he was turned to be their enemy, and he fought against them.

The word translated “vexed” grows from the same root as pain, linking rebellion to a wound that gives way to conflict.

When the set-apart breath is resisted, the relationship is wounded and opposition follows. The verse holds grief and conflict together: this presence is not indifferent to rebellion.

WHAT THIS UNDOES

The belief that rebellion leaves the relationship untouched dissolves here: the verse names grief and opposition as its consequences.

וְעִצְּבוּ

ve'itssevu

GROWS FROM

עצב

atsav

To cause pain or grief.

“pained” in this verse is ve'itssevu. The verb translated “vexed” comes from the same root that names pain and painful toil, so this is more than irritation: rebellion wounds the relationship. The grief of the set-apart breath and the ensuing conflict belong to one movement.

ALSO GROWS

etsev: Pain, sorrow, or toil.

עֶצֶב

The shared root links grieving with felt pain, giving “vexed” a weight deeper than annoyance.

itsavon: Painful toil or sorrow.

עִצָּבוֹן

This branch shows the root extending into sustained pain, echoing the relational wound named here.

מָרוּ

maru

GROWS FROM

מרה

marah

To resist or rebel.

“rebelled” in this verse is maru. The same seed appears in words for rebellion and for a rebellious person. Resistance here is a posture that shapes the relationship, not a passing disturbance.

ALSO GROWS

meri: Rebellion or resistance.

מְרִי

The noun makes explicit the quality carried by the verb: this is active opposition.

moreh: A rebellious or disobedient person.

מוֹרֶה

The branch describes a person by the resisting posture that the verse names.

קָדְשׁוֹ

qodsho

GROWS FROM

קדש

qadash

To set apart as sacred.

“Set-Apart Breath” in this verse is qodsho. The word rendered “holy” shares its root with words for holiness and sanctuary. The breath is presented as a set-apart presence, so its grief is not an impersonal reaction.

ALSO GROWS

qodesh: Holiness; that which is set apart as sacred.

קֹדֶשׁ

This branch clarifies the quality attached to the breath: it is set apart.

miqdash: Sanctuary or sacred place.

מִקְדָּשׁ

The shared root connects set-apartness with a presence marked as sacred space.

Resistance to the divine presence is portrayed as a wound within a relationship, not a neutral act.

How often they strained against him in the wilderness, and made him ache in the barren place!
Psalm 78:40 · SDVThe verse pairs resistance with grief, echoing Isaiah’s account of a wounded relationship.
And do not hurt the Set-Apart Breath of God, in whom you have been sealed for the day of release.
Ephesians 4:30 · SDVThe set-apart Spirit is again described as someone who can be grieved, not as an impersonal force.
Therefore I was sickened by that generation, and said, They always wander in their heart, and they have not known my ways.
Hebrews 3:10 · SDVThe text joins a people’s resistance with divine grief, repeating the relational pattern.
How often they strained against him in the wilderness, and made him ache in the barren place!
Psalm 78:40 · SDV

Psalm 78 uses the same Hebrew root for “grieve” that Isaiah uses for “vexed.” The shared root ties both verses to pain within the relationship, opening Isaiah’s grief as more than mere displeasure.

This reading is from Selah Verse.

You can read any verse this way in the app, keep it as a card, and send it on.

Get Selah Verse

A Bible app where you send verses from your keyboard and in Messages, and every verse has a Deep Dive.

Does something in this reading look wrong? Tell us

Isaiah 63:10 Meaning